EXHIBIT ID: BR_C_0384

Progression of Meningitis and Vasculitis

Progression of Meningitis and Vasculitis

Anterior view of the brain showing how bacteria gaining access to the subdural space, attach to the vascular endothelium leading to invasion and proliferaton of bacteria in the the cerebral spinal fluid. Antibiotics are introduced killing the bacteria, but resulting in a release of toxin that lead to inflammation of the vessels (vasculitis) and the formation of a thrombus