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EXHIBIT ID: BR_A_1011

Cerebral Ischemia and Global Brain Injury

Animation showing widespread cerebral ischemia as a result of a lack of oxygen due to an umbilical accident, and the resulting reperfusion injury when oxygen in restored.

BR_A_1011 brain cerebral ischemia global injury baby placenta umbilical cord arteries vein heart aorta common carotid internal normal fetal oxygenation right left middle artery cerebellum cerebrum tissue reperfusion dilated fluid leak swelling compression